High-throughput method for analyzing methylation of CpGs in targeted genomic regions

A unique microarray-based method for determining the extent of DNA methylation has been developed. It relies on a selective enrichment of the regions to be assayed by target amplification by capture and ligation (mTACL). The assay is quantitatively accurate, relatively precise, and lends itself to h...

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Autori principali: Nautiyal, Shivani, Carlton, Victoria E. H., Lu, Yontao, Ireland, James S., Flaucher, Diane, Moorhead, Martin, Gray, Joe W., Spellman, Paul, Mindrinos, Michael, Berg, Paul, Faham, Malek
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906552/
https://ncbi.nlm.nih.gov/pubmed/20616066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005173107
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