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Prediction of epigenetically regulated genes in breast cancer cell lines

BACKGROUND: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation of CpG islands may silence associated genes. Therefore, using high-throughput microarrays to measure CpG island methylatio...

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Detalhes bibliográficos
Main Authors: Loss, Leandro A, Sadanandam, Anguraj, Durinck, Steffen, Nautiyal, Shivani, Flaucher, Diane, Carlton, Victoria EH, Moorhead, Martin, Lu, Yontao, Gray, Joe W, Faham, Malek, Spellman, Paul, Parvin, Bahram
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903569/
https://ncbi.nlm.nih.gov/pubmed/20525369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-305
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