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No CpGs for AAVs?

In this issue of Blood, Konkle et al report that 7 of 8 participants in a phase 1/2 trial of adeno-associated virus (AAV) vector (BAX335) for factor IX (FIX)-Padua gene transfer in patients with hemophilia B did not maintain expression despite steroid intervention, which the authors hypothesize is a...

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Dades bibliogràfiques
Publicat a:Blood
Autor principal: George, Lindsey A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885819/
https://ncbi.nlm.nih.gov/pubmed/33570612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009285
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