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Mapping nucleosome position at single base-pair resolution by using site-directed hydroxyl radicals.

A base-pair resolution method for determining nucleosome position in vitro has been developed to com- plement existing, less accurate methods. Cysteaminyl EDTA was tethered to a recombinant histone octamer via a mutant histone H4 with serine 47 replaced by cysteine. When assembled into nucleosome co...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Flaus, A, Luger, K, Tan, S, Richmond, T J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39944/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1370
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