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Single-base resolution mapping of 5-hydroxymethylcytosine modifications in hippocampus of Alzheimer’s disease subjects

Epigenetic modifications to cytosine have been shown to regulate transcription in cancer, embryonic development, and recently neurodegeneration. While cytosine methylation studies are now common in neurodegenerative research, hydroxymethylation studies are rare, particularly genome-wide mapping stud...

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Detalhes bibliográficos
Publicado no:J Mol Neurosci
Main Authors: Ellison, Elizabeth M., Bradley-Whitman, Melissa A., Lovell, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909840/
https://ncbi.nlm.nih.gov/pubmed/28866733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-017-0969-y
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