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Single-base resolution mapping of 5-hydroxymethylcytosine modifications in hippocampus of Alzheimer’s disease subjects

Epigenetic modifications to cytosine have been shown to regulate transcription in cancer, embryonic development, and recently neurodegeneration. While cytosine methylation studies are now common in neurodegenerative research, hydroxymethylation studies are rare, particularly genome-wide mapping stud...

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Bibliografske podrobnosti
izdano v:J Mol Neurosci
Main Authors: Ellison, Elizabeth M., Bradley-Whitman, Melissa A., Lovell, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909840/
https://ncbi.nlm.nih.gov/pubmed/28866733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-017-0969-y
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