טוען...

Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution

Hydrogen bonds between backbone amide groups of enzymes and their substrates are often observed, but their importance in substrate binding and/or catalysis is not easy to investigate experimentally. We describe the generation and kinetic characterization of a backbone amide to ester substitution in...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Desai, Bijoy J., Goto, Yuki, Cembran, Alessandro, Fedorov, Alexander A., Almo, Steven C., Gao, Jiali, Suga, Hiroaki, Gerlt, John A.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210302/
https://ncbi.nlm.nih.gov/pubmed/25275007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411772111
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!