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Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors
Control over the sensitivity with which biomolecular receptors respond to small changes in the concentration of their target ligand is critical for the proper function of many cellular processes. Such control could likewise be of utility in artificial biotechnologies, such as biosensors, genetic log...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210277/ https://ncbi.nlm.nih.gov/pubmed/25288724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410796111 |
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