Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function

cAMP signaling in the brain mediates several higher order neural processes. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels directly bind cAMP through their cytoplasmic cyclic nucleotide binding domain (CNBD), thus playing a unique role in brain function. Neuronal HCN channels are...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Saponaro, Andrea, Pauleta, Sofia R., Cantini, Francesca, Matzapetakis, Manolis, Hammann, Christian, Donadoni, Chiara, Hu, Lei, Thiel, Gerhard, Banci, Lucia, Santoro, Bina, Moroni, Anna
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210022/
https://ncbi.nlm.nih.gov/pubmed/25197093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410389111
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker