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A reduced mechanical model for cAMP-modulated gating in HCN channels
We developed an in silico mechanical model to analyze the process of cAMP-induced conformational modulations in hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, which conduct cations across the membrane of mammalian heart and brain cells. The structural analysis reveals a quaterna...
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| Foilsithe in: | Sci Rep |
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| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225470/ https://ncbi.nlm.nih.gov/pubmed/28074902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40168 |
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