Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation

Lignende værker

• Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study
  af: Telesco, Shannon E., et al.
  Udgivet: (2009)
• Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases
  af: Shih, Andrew J., et al.
  Udgivet: (2011)
• A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network
  af: Telesco, Shannon E., et al.
  Udgivet: (2011)
• Molecular Modeling of the ErbB4/HER4 Kinase in the Context of the HER4 Signaling Network Helps Rationalize the Effects of Clinically Identified HER4 Somatic Mutations on the Cell Phenotype
  af: Telesco, Shannon E., et al.
  Udgivet: (2013)
• Computational Delineation of Tyrosyl-Substrate Recognition and Catalytic Landscapes in the Epidermal Growth Factor Receptor Tyrosine Kinase Domain
  af: Liu, Yingting, et al.
  Udgivet: (2014)