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Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates
Many neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by abnormal accumulations of aggregated proteins. Brains in these diseases also show accumulation of autophagic vesicles in the neuronal cytoplasm, suggesting impairment of the autophagi...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207479/ https://ncbi.nlm.nih.gov/pubmed/24632948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.30 |
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