Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates

Many neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by abnormal accumulations of aggregated proteins. Brains in these diseases also show accumulation of autophagic vesicles in the neuronal cytoplasm, suggesting impairment of the autophagi...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Bae, E-J, Lee, H-J, Jang, Y-H, Michael, S, Masliah, E, Min, D S, Lee, S-J
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2014
Ábhair:
Original Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207479/
https://ncbi.nlm.nih.gov/pubmed/24632948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.30
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla