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Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates

Many neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are characterized by abnormal accumulations of aggregated proteins. Brains in these diseases also show accumulation of autophagic vesicles in the neuronal cytoplasm, suggesting impairment of the autophagi...

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Bibliografske podrobnosti
Main Authors: Bae, E-J, Lee, H-J, Jang, Y-H, Michael, S, Masliah, E, Min, D S, Lee, S-J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207479/
https://ncbi.nlm.nih.gov/pubmed/24632948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.30
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