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Is trehalose an autophagic inducer? Unraveling the roles of non-reducing disaccharides on autophagic flux and alpha-synuclein aggregation

Autophagy is a pivotal intracellular process by which cellular macromolecules are degraded upon various stimuli. A failure in the degradation of autophagic substrates such as impaired organelles and protein aggregates leads to their accumulations, which are characteristics of many neurodegenerative...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Death Dis
Main Authors: Yoon, Ye-Seul, Cho, Eun-Duk, Jung Ahn, Woo, Won Lee, Kyung, Lee, Seung-Jae, Lee, He-Jin
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682667/
https://ncbi.nlm.nih.gov/pubmed/28981090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.501
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