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Alpha-Synuclein Inclusion Formation in Human Oligodendrocytes

Multiple system atrophy (MSA) is a neurodegenerative disease characterized by presence of α-synuclein-positive inclusions in the cytoplasm of oligodendrocytes. These glial cytoplasmic inclusions (GCIs) are considered an integral part of the pathogenesis of MSA, leading to demyelination and neuronal...

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Publicado en:Biomol Ther (Seoul)
Autores principales: Yoon, Ye-Seul, Ahn, Woo Jung, Ricarte, Diadem, Ortiz, Darlene, Shin, Chan Young, Lee, Seung-Jae, Lee, He-Jin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Korean Society of Applied Pharmacology 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7771843/
https://ncbi.nlm.nih.gov/pubmed/32536617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2020.081
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