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Dopamine promotes formation and secretion of non-fibrillar alpha-synuclein oligomers

Parkinson's disease (PD) is characterized by selective and progressive degeneration of dopamine (DA)-producing neurons in the substantia nigra pars compacta (SNpc) and by abnormal aggregation of α-synuclein. Previous studies have suggested that DA can interact with α-synuclein, thus modulating...

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Detalhes bibliográficos
Main Authors: Lee, He-Jin, Baek, Sung Min, Ho, Dong-Hwan, Suk, Ji-Eun, Cho, Eun-Duk, Lee, Seung-Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085740/
https://ncbi.nlm.nih.gov/pubmed/21415592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.4.026
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