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Autophagic failure promotes the exocytosis and intercellular transfer of α-synuclein
The accumulation of abnormal protein aggregates is a major characteristic of many neurodegenerative disorders, including Parkinson's disease (PD). The intracytoplasmic deposition of α-synuclein aggregates and Lewy bodies, often found in PD and other α-synucleinopathies, is thought to be linked...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674407/ https://ncbi.nlm.nih.gov/pubmed/23661100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.45 |
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