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Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis
Intrinsic apoptotic stimuli initiate mammalian cells’ apoptotic program by first activating the proteins that have only Bcl-2 homology domain 3 (BH3), such as Bcl-2 interacting mediator of cell death (Bim) and truncated BH3 interacting death domain agonist (tBid), which in turn trigger conformationa...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205663/ https://ncbi.nlm.nih.gov/pubmed/25275009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417253111 |
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