Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

Mitochondria are functionally and physically associated with heterotypic membranes, yet little is known about how these interactions impact mitochondrial outer-membrane permeabilization (MOMP) and apoptosis. We observed that dissociation of heterotypic membranes from mitochondria inhibited BAK/BAX-d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chipuk, Jerry E., McStay, Gavin P., Bharti, Archana, Kuwana, Tomomi, Clarke, Christopher J., Siskind, Leah J., Obeid, Lina M., Green, Douglas R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506012/
https://ncbi.nlm.nih.gov/pubmed/22385963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.038
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