Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis

Mitochondria are functionally and physically associated with heterotypic membranes, yet little is known about how these interactions impact mitochondrial outer-membrane permeabilization (MOMP) and apoptosis. We observed that dissociation of heterotypic membranes from mitochondria inhibited BAK/BAX-d...

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Bibliografiset tiedot
Päätekijät: Chipuk, Jerry E., McStay, Gavin P., Bharti, Archana, Kuwana, Tomomi, Clarke, Christopher J., Siskind, Leah J., Obeid, Lina M., Green, Douglas R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3506012/
https://ncbi.nlm.nih.gov/pubmed/22385963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.038
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