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BAK/BAX activation and cytochrome c release assays using isolated mitochondria
The mitochondrial pathway of apoptosis proceeds when the outer mitochondrial membrane (OMM) is compromised by the pro-apoptotic BCL-2 family members, BAK and BAX. Once activated, BAK and BAX form proteolipid pores in the OMM leading to mitochondrial outer membrane permeabilization (MOMP), and the re...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3686896/ https://ncbi.nlm.nih.gov/pubmed/23567751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.03.030 |
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