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Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis

Intrinsic apoptotic stimuli initiate mammalian cells’ apoptotic program by first activating the proteins that have only Bcl-2 homology domain 3 (BH3), such as Bcl-2 interacting mediator of cell death (Bim) and truncated BH3 interacting death domain agonist (tBid), which in turn trigger conformationa...

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書誌詳細
主要な著者: Jiang, Xian, Jiang, Hui, Shen, Zhirong, Wang, Xiaodong
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205663/
https://ncbi.nlm.nih.gov/pubmed/25275009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417253111
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