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Pseudomonas aeruginosa Homoserine Lactone Triggers Apoptosis and Bak/Bax-Independent Release of Mitochondrial Cytochrome C in Fibroblasts
Pseudomonas aeruginosa use N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule to regulate gene expression in the bacteria. It is expected that in patients with chronic infections with P. aeruginosa, especially as biofilms, local [C12] will be high and, since C12 is lipid solub...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065231/ https://ncbi.nlm.nih.gov/pubmed/24438098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12263 |
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