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Pseudomonas aeruginosa Quorum-Sensing Molecule Homoserine Lactone Modulates Inflammatory Signaling through PERK and eI-F2α()
Pseudomonas aeruginosa (PA) secrete N-(3-oxododecanoyl)-homoserine lactone (HSL-C12) as a quorum-sensing molecule to regulate bacterial gene expression. Since HSL-C12 is membrane-permeant, multiple cell types in PA-infected airways may be exposed to HSL-C12, especially adjacent to biofilms where loc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113911/ https://ncbi.nlm.nih.gov/pubmed/24990083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303437 |
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