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N-(3-oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts

N-(3-oxododecanoyl)-homoserine lactone (C12) is produced by Pseudomonas aeruginosa to function as a quorum-sensing molecule for bacteria-bacteria communication. C12 is also known to influence many aspects of human host cell physiology, including induction of cell death. However, the signaling pathwa...

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Dades bibliogràfiques
Publicat a:Cell Microbiol
Autors principals: Neely, Aaron M., Zhao, Guoping, Schwarzer, Christian, Stivers, Nicole S., Whitt, Aaron G., Meng, Shuhan, Burlison, Joseph A., Machen, Terry E., Li, Chi
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5729120/
https://ncbi.nlm.nih.gov/pubmed/28876505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12787
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