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Pseudomonas aeruginosa Homoserine Lactone Triggers Apoptosis and Bak/Bax-Independent Release of Mitochondrial Cytochrome C in Fibroblasts

Pseudomonas aeruginosa use N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule to regulate gene expression in the bacteria. It is expected that in patients with chronic infections with P. aeruginosa, especially as biofilms, local [C12] will be high and, since C12 is lipid solub...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schwarzer, Christian, Fu, Zhu, Shuai, Stacey, Babbar, Salil, Zhao, Guoping, Li, Chi, Machen, Terry E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065231/
https://ncbi.nlm.nih.gov/pubmed/24438098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12263
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