Bak Compensated for Bax in p53-null Cells to Release Cytochrome c for the Initiation of Mitochondrial Signaling during Withanolide D-Induced Apoptosis

The goal of cancer chemotherapy to induce multi-directional apoptosis as targeting a single pathway is unable to decrease all the downstream effect arises from crosstalk. Present study reports that Withanolide D (WithaD), a steroidal lactone isolated from Withania somnifera, induced cellular apoptos...

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Hlavní autoři: Mondal, Susmita, Bhattacharya, Kaushik, Mallick, Asish, Sangwan, Rajender, Mandal, Chitra
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315518/
https://ncbi.nlm.nih.gov/pubmed/22479585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034277
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