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A thermodynamic perspective on the dock-lock growth mechanism of amyloid fibrils
The mechanism of addition of a soluble unstructured monomer to a preformed ordered amyloid fibril is a complex process. Based on the kinetics of monomer disassociation of Aβ(1 — 40) from the amyloid fibril, it has been suggested that deposition is a multi-step process involving a rapid reversible as...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4204656/ https://ncbi.nlm.nih.gov/pubmed/19813700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp9050098 |
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