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Dynamics of locking of peptides onto growing amyloid fibrils

Sequence-dependent variations in the growth mechanism and stability of amyloid fibrils, which are implicated in a number of neurodegenerative diseases, are poorly understood. We have carried out extensive all-atom molecular dynamics simulations to monitor the structural changes that occur upon addit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Reddy, Govardhan, Straub, John E., Thirumalai, D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715474/
https://ncbi.nlm.nih.gov/pubmed/19581575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902473106
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