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Dynamics of locking of peptides onto growing amyloid fibrils
Sequence-dependent variations in the growth mechanism and stability of amyloid fibrils, which are implicated in a number of neurodegenerative diseases, are poorly understood. We have carried out extensive all-atom molecular dynamics simulations to monitor the structural changes that occur upon addit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715474/ https://ncbi.nlm.nih.gov/pubmed/19581575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902473106 |
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