Učitavanje...
Elucidating the Locking Mechanism of Peptides onto Growing Amyloid Fibrils through Transition Path Sampling
We investigate the molecular mechanism of monomer addition to a growing amyloid fibril composed of the main amyloidogenic region from the insulin peptide hormone, the LVEALYL heptapeptide. Applying transition path sampling in combination with reaction coordinate analysis reveals that the transition...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3446680/ https://ncbi.nlm.nih.gov/pubmed/22995502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.056 |
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