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Structural Transitions and Interactions in the Early Stages of Human Glucagon Amyloid Fibrillation
A mechanistic understanding of the intermolecular interactions and structural changes during fibrillation is crucial for the design of safe and efficacious glucagon formulations. Amide hydrogen/deuterium exchange with mass spectrometric analysis was used to identify the interactions and amino acids...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336368/ https://ncbi.nlm.nih.gov/pubmed/25692598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.01.004 |
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