The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

Activated B cells undergo immunoglobulin class-switch recombination (CSR) and differentiate into antibody-secreting plasma cells. The distinct transcriptomes of B cells and plasma cells are maintained by the antagonistic influences of two groups of transcription factors: those that maintain the B ce...

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Библиографические подробности
Главные авторы: Carotta, Sebastian, Willis, Simon N., Hasbold, Jhagvaral, Inouye, Michael, Pang, Swee Heng Milon, Emslie, Dianne, Light, Amanda, Chopin, Michael, Shi, Wei, Wang, Hongsheng, Morse, Herbert C., Tarlinton, David M., Corcoran, Lynn M., Hodgkin, Philip D., Nutt, Stephen L.
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203955/
https://ncbi.nlm.nih.gov/pubmed/25288399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140425
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