PU.1 cooperates with IRF4 and IRF8 to suppress pre-B cell leukemia

The Ets family transcription factor PU.1 and the interferon regulatory factor (IRF)4 and IRF8 regulate gene expression by binding to composite DNA sequences known as Ets/interferon consensus elements (EICE). Although all three factors are expressed from the onset of B cell development, single defici...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Pang, Swee Heng Milon, Minnich, Martina, Gangatirkar, Pradnya, Zheng, Zhiqiang, Ebert, Anja, Song, Guangchun, Dickins, Ross A, Corcoran, Lynn M, Mullighan, Charles G., Busslinger, Meinrad, Huntington, Nicholas D, Nutt, Stephen L, Carotta, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179358/
https://ncbi.nlm.nih.gov/pubmed/26932576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.27
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