Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73

Dysregulation of cellular transcription and translation is a fundamental hallmark of cancer. As CDK9 and Mnks play pivotal roles in the regulation of RNA transcription and protein synthesis, respectively, they are important targets for drug development. We herein report the cellular mechanism of a n...

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Main Authors: Lam, Frankie, Abbas, Abdullahi Y., Shao, Hao, Teo, Theodosia, Adams, Julian, Li, Peng, Bradshaw, Tracey D., Fischer, Peter M., Walsby, Elisabeth, Pepper, Chris, Chen, Yi, Ding, Jian, Wang, Shudong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2014
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202154/
https://ncbi.nlm.nih.gov/pubmed/25277198
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