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Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73

Dysregulation of cellular transcription and translation is a fundamental hallmark of cancer. As CDK9 and Mnks play pivotal roles in the regulation of RNA transcription and protein synthesis, respectively, they are important targets for drug development. We herein report the cellular mechanism of a n...

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Autori principali: Lam, Frankie, Abbas, Abdullahi Y., Shao, Hao, Teo, Theodosia, Adams, Julian, Li, Peng, Bradshaw, Tracey D., Fischer, Peter M., Walsby, Elisabeth, Pepper, Chris, Chen, Yi, Ding, Jian, Wang, Shudong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202154/
https://ncbi.nlm.nih.gov/pubmed/25277198
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