Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73

Dysregulation of cellular transcription and translation is a fundamental hallmark of cancer. As CDK9 and Mnks play pivotal roles in the regulation of RNA transcription and protein synthesis, respectively, they are important targets for drug development. We herein report the cellular mechanism of a n...

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Detalhes bibliográficos
Main Authors: Lam, Frankie, Abbas, Abdullahi Y., Shao, Hao, Teo, Theodosia, Adams, Julian, Li, Peng, Bradshaw, Tracey D., Fischer, Peter M., Walsby, Elisabeth, Pepper, Chris, Chen, Yi, Ding, Jian, Wang, Shudong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202154/
https://ncbi.nlm.nih.gov/pubmed/25277198
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