CDKI-73 Is a Novel Pharmacological Inhibitor of Rab11 Cargo Delivery and Innate Immune Secretion

Innate immunity is critical for host defence against pathogen and environmental challenge and this involves the production and secretion of immune mediators, such as antimicrobial peptides and pro-inflammatory cytokines. However, when dysregulated, innate immunity can contribute to multifactorial di...

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Detalhes bibliográficos
Main Authors: Alexandra Sorvina, Tetyana Shandala, Shudong Wang, David J. Sharkey, Emma Parkinson-Lawrence, Stavros Selemidis, Douglas A. Brooks
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
Colecção:Cells
Assuntos:
cdki-73
endosomes
rab11
antimicrobial peptide drosomycin
il-6
tnfα
<i>drosophila</i>
Acesso em linha:https://www.mdpi.com/2073-4409/9/2/372
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