βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

In mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the regulation of the G2/M transition, G1 progression and G1/S transition. CDK1 is highly regulated by its association to cyclins, phosphorylation and dephosphorylation, changes in...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Herrero-Ruiz, Joaquín, Mora-Santos, Mar, Giráldez, Servando, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202144/
https://ncbi.nlm.nih.gov/pubmed/25149538
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki