βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

In mammals, cell cycle progression is controlled by cyclin-dependent kinases, among which CDK1 plays important roles in the regulation of the G2/M transition, G1 progression and G1/S transition. CDK1 is highly regulated by its association to cyclins, phosphorylation and dephosphorylation, changes in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Herrero-Ruiz, Joaquín, Mora-Santos, Mar, Giráldez, Servando, Sáez, Carmen, Japón, Miguel Á., Tortolero, Maria, Romero, Francisco
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2014
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202144/
https://ncbi.nlm.nih.gov/pubmed/25149538
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk