Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation

The pathophysiological events that lead to renal interstitial fibrogenesis are incompletely understood. Epoxyeicosatrienoic acid (EET), an arachidonic acid metabolite, has anti-inflammatory and profibrinolytic functions. Soluble epoxide hydrolase (sEH) converts EET to less active dihydroxyeicosatrie...

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Bibliographic Details
Main Authors: Kim, Jinu, Imig, John D., Yang, Jun, Hammock, Bruce D., Padanilam, Babu J.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200297/
https://ncbi.nlm.nih.gov/pubmed/25164080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00256.2014
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