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Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation
The pathophysiological events that lead to renal interstitial fibrogenesis are incompletely understood. Epoxyeicosatrienoic acid (EET), an arachidonic acid metabolite, has anti-inflammatory and profibrinolytic functions. Soluble epoxide hydrolase (sEH) converts EET to less active dihydroxyeicosatrie...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200297/ https://ncbi.nlm.nih.gov/pubmed/25164080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00256.2014 |
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