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Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy

Treating chronic kidney disease (CKD) has been challenging because of its pathogenic complexity. Epoxyeicosatrienoic acids (EETs) are cytochrome P-450-dependent derivatives of arachidonic acid with antihypertensive, anti-inflammatory, and profibrinolytic functions. We recently reported that genetic...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Kim, Jinu, Yoon, Sang Pil, Toews, Myron L., Imig, John D., Hwang, Sung Hee, Hammock, Bruce D., Padanilam, Babu J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338924/
https://ncbi.nlm.nih.gov/pubmed/25377915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00531.2014
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