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Soluble Epoxide Hydrolase as a Therapeutic Target for Cardiovascular Diseases
Cardiovascular effects of epoxyeicosatrienoic acids (EETs) include vasodilation, vascular smooth muscle cell anti-migratory actions, and anti-inflammatory actions. These endogenous lipid mediators are broken down to diols by soluble epoxide hydrolase (sEH), and so inhibiting this enzyme would be exp...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021468/ https://ncbi.nlm.nih.gov/pubmed/19794443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2875 |
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