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Soluble Epoxide Hydrolase as a Therapeutic Target for Pain, Inflammatory and Neurodegenerative Diseases

Eicosanoids are biologically active lipid signaling molecules derived from polyunsaturated fatty acids. Many of the actions of eicosanoid metabolites formed by cyclooxygenase and lipoxygenase enzymes have been characterized, however, the epoxy-fatty acids (EpFAs) formed by cytochrome P450 enzymes ar...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Wagner, Karen M., McReynolds, Cindy B., Schmidt, William K., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677555/
https://ncbi.nlm.nih.gov/pubmed/28642117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.06.006
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