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Soluble epoxide hydrolase: a novel therapeutic target in stroke

The P450 eicosanoids epoxyeicosatrienoic acids (EETs) are produced in brain and perform important biological functions, including protection from ischemic injury. The beneficial effect of EETs, however, is limited by their metabolism via soluble epoxide hydrolase (sEH). We tested the hypothesis that...

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Main Authors: Zhang, Wenri, Koerner, Ines P, Noppens, Ruediger, Grafe, Marjorie, Tsai, Hsing-Ju, Morisseau, Christophe, Luria, Ayala, Hammock, Bruce D, Falck, John R, Alkayed, Nabil J
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664093/
https://ncbi.nlm.nih.gov/pubmed/17440491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600494
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