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Soluble epoxide hydrolase: a novel therapeutic target in stroke

The P450 eicosanoids epoxyeicosatrienoic acids (EETs) are produced in brain and perform important biological functions, including protection from ischemic injury. The beneficial effect of EETs, however, is limited by their metabolism via soluble epoxide hydrolase (sEH). We tested the hypothesis that...

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Detalhes bibliográficos
Main Authors: Zhang, Wenri, Koerner, Ines P, Noppens, Ruediger, Grafe, Marjorie, Tsai, Hsing-Ju, Morisseau, Christophe, Luria, Ayala, Hammock, Bruce D, Falck, John R, Alkayed, Nabil J
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664093/
https://ncbi.nlm.nih.gov/pubmed/17440491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600494
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