Chargement en cours...
Peptidyl-urea based inhibitors of soluble epoxide hydrolases
We prepared a series of amino acid derived cyclohexyl and adamantyl ureas and tested them as inhibitors of the human soluble epoxide hydrolase, and obtained very potent compounds (K(I) = 15 nM) that are >10-fold more soluble than previously described sEH inhibitors. While our lead compound 2 show...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892215/ https://ncbi.nlm.nih.gov/pubmed/16908134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.07.073 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|