Llwytho...

Optimization of Amide-Based Inhibitors of Soluble Epoxide Hydrolase with Improved Water Solubility

Soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation. 1,3-Disubstituted ureas with a polar group located on the fifth atom from the carbonyl group of urea function are active inhibitor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, In-Hae, Heirtzler, Fenton R., Morisseau, Christophe, Nishi, Kosuke, Tsai, Hsing-Ju, Hammock, Bruce D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450255/
https://ncbi.nlm.nih.gov/pubmed/15887969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0500929
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