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Peroxisomal translocation of soluble epoxide hydrolase protects against ischemic stroke injury

Soluble epoxide hydrolase (sEH) contributes to cardiovascular disease, including stroke, although the exact mechanism remains unclear. While primarily a cytosolic enzyme, sEH can translocate into peroxisomes. The relevance of this for stroke injury is not understood. We tested the hypothesis that sE...

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Pubblicato in:J Cereb Blood Flow Metab
Autori principali: Nelson, Jonathan W, Zhang, Wenri, Alkayed, Nabil J, Koerner, Ines P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4640333/
https://ncbi.nlm.nih.gov/pubmed/26126869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2015.159
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