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Homologous Recombination Is a Primary Pathway to Repair DNA Double-Strand Breaks Generated during DNA Rereplication

Re-initiation of DNA replication at origins within a given cell cycle would result in DNA rereplication, which can lead to genome instability and tumorigenesis. DNA rereplication can be induced by loss of licensing control at cellular replication origins, or by viral protein-driven multiple rounds o...

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Bibliografische gegevens
Hoofdauteurs: Truong, Lan N., Li, Yongjiang, Sun, Emily, Ang, Katrina, Hwang, Patty Yi-Hwa, Wu, Xiaohua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200250/
https://ncbi.nlm.nih.gov/pubmed/25160628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576488
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