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Homologous Recombination Is a Primary Pathway to Repair DNA Double-Strand Breaks Generated during DNA Rereplication

Re-initiation of DNA replication at origins within a given cell cycle would result in DNA rereplication, which can lead to genome instability and tumorigenesis. DNA rereplication can be induced by loss of licensing control at cellular replication origins, or by viral protein-driven multiple rounds o...

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Hlavní autoři: Truong, Lan N., Li, Yongjiang, Sun, Emily, Ang, Katrina, Hwang, Patty Yi-Hwa, Wu, Xiaohua
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200250/
https://ncbi.nlm.nih.gov/pubmed/25160628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576488
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