Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Microhomology-mediated end joining (MMEJ) is a major pathway for Ku-independent alternative nonhomologous end joining, which contributes to chromosomal translocations and telomere fusions, but the underlying mechanism of MMEJ in mammalian cells is not well understood. In this study, we demonstrated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Truong, Lan N., Li, Yongjiang, Shi, Linda Z., Hwang, Patty Yi-Hwa, He, Jing, Wang, Hailong, Razavian, Niema, Berns, Michael W., Wu, Xiaohua
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651503/
https://ncbi.nlm.nih.gov/pubmed/23610439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213431110
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