Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Microhomology-mediated end joining (MMEJ) is a major pathway for Ku-independent alternative nonhomologous end joining, which contributes to chromosomal translocations and telomere fusions, but the underlying mechanism of MMEJ in mammalian cells is not well understood. In this study, we demonstrated...

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Detalles Bibliográficos
Main Authors: Truong, Lan N., Li, Yongjiang, Shi, Linda Z., Hwang, Patty Yi-Hwa, He, Jing, Wang, Hailong, Razavian, Niema, Berns, Michael W., Wu, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651503/
https://ncbi.nlm.nih.gov/pubmed/23610439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213431110
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