Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Microhomology-mediated end joining (MMEJ) is a major pathway for Ku-independent alternative nonhomologous end joining, which contributes to chromosomal translocations and telomere fusions, but the underlying mechanism of MMEJ in mammalian cells is not well understood. In this study, we demonstrated...

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Détails bibliographiques
Auteurs principaux: Truong, Lan N., Li, Yongjiang, Shi, Linda Z., Hwang, Patty Yi-Hwa, He, Jing, Wang, Hailong, Razavian, Niema, Berns, Michael W., Wu, Xiaohua
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651503/
https://ncbi.nlm.nih.gov/pubmed/23610439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213431110
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